The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 07, 2015

Filed:

Apr. 01, 2013
Applicant:

University of Louisville Research Foundation, Inc., Louisville, KY (US);

Inventors:

Mohammadrreza Negahdar, Louisville, KY (US);

Amir A. Amini, Louisville, KY (US);

Neal Dunlap, Louisville, KY (US);

Shiao Woo, Louisville, KY (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
G06T 7/00 (2006.01);
U.S. Cl.
CPC ...
G06T 7/0024 (2013.01); G06T 7/0012 (2013.01); G06T 2207/10076 (2013.01); G06T 2207/10081 (2013.01); G06T 2207/30061 (2013.01);
Abstract

A method of deformable image registration for thoracic 4-D computed tomography (CT) images includes: receiving, by a processing device, a set of thoracic 4-D CT images; and iteratively solving, by the processing device, an energy function applied to subsequent images of the set of thoracic 4-D CT images to transform the subsequent images into respective optical flow fields between the subsequent images, the energy function enforcing the following constraints on the subsequent images: intensity constancy; mass conservation; gradient constancy; and spatio-temporal smoothness. A method of determining regional lung function includes: receiving, by a processing device, a set of thoracic 4-D CT images of a lung; transforming, by the processing device, the set of 4-D CT images of the lung into respective spatial voxel-wise deformation maps; and transforming, by the processing device, the spatial voxel-wise deformation maps into respective spatial voxel-wise strain maps of the lung indicating regional mechanics of the lung.


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