The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 07, 2015

Filed:

Sep. 01, 2011
Applicants:

Ramanaiah C. Kanamarlapudi, Bridgewater, NJ (US);

Steven A. Weissman, Short Hills, NJ (US);

Emerich Eisenreich, Claremont, CA (US);

Xuejun Liu, Arcadia, CA (US);

Inventors:

Ramanaiah C. Kanamarlapudi, Bridgewater, NJ (US);

Steven A. Weissman, Short Hills, NJ (US);

Emerich Eisenreich, Claremont, CA (US);

Xuejun Liu, Arcadia, CA (US);

Assignee:

Concert Pharmaceuticals, Inc., Lexington, MA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C12P 17/18 (2006.01); C07B 35/02 (2006.01); C07D 473/10 (2006.01); C07B 59/00 (2006.01);
U.S. Cl.
CPC ...
C12P 17/182 (2013.01); C07B 59/002 (2013.01); C07D 473/10 (2013.01);
Abstract

The present invention provides a process for the preparation of enantiomerically enriched, deuterated secondary alcohols of Formula 1-A by employing ketoreductases or carbonyl reductases without reducing deuterium incorporation.


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