The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 07, 2015

Filed:

Sep. 16, 2013
Applicants:

Martin Gleave, Vancouver, CA;

Paul S. Rennie, Richmond, CA;

Hideaki Miyake, Vancouver, CA;

Colleen Nelson, Surrey, CA;

Inventors:

Martin Gleave, Vancouver, CA;

Paul S. Rennie, Richmond, CA;

Hideaki Miyake, Vancouver, CA;

Colleen Nelson, Surrey, CA;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/113 (2010.01); A61K 31/00 (2006.01); A61K 31/337 (2006.01); A61K 31/66 (2006.01); A61K 31/704 (2006.01); A61K 41/00 (2006.01); A61K 45/06 (2006.01); C07H 21/00 (2006.01); C07K 14/775 (2006.01); A61K 48/00 (2006.01);
U.S. Cl.
CPC ...
C12N 15/1135 (2013.01); A61K 31/00 (2013.01); A61K 31/337 (2013.01); A61K 31/66 (2013.01); A61K 31/704 (2013.01); A61K 41/0038 (2013.01); A61K 45/06 (2013.01); A61K 48/00 (2013.01); C07H 21/00 (2013.01); C07K 14/775 (2013.01); C12N 15/113 (2013.01); C12N 2310/315 (2013.01); C12N 2310/321 (2013.01); C12N 2310/3341 (2013.01); C12N 2310/341 (2013.01); C12N 2310/346 (2013.01);
Abstract

A method for treating an individual suffering from a cancer comprising administering to the individual i) a chemotherapeutic agent, and ii) one antisense oligonucleotide having nucleotides in the sequence set forth in Seq. ID No. 4 and which antisense oligonucleotide has a phosphorothioate modification that increases the stability thereof in vivo, wherein the cancer expresses testosterone-repressed prostate message-2 (TRPM-2), thereby treating said individual.


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