The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 07, 2015
Filed:
Nov. 17, 2011
Applicants:
Jun Yamashita, Kyoto, JP;
Hideki Uosaki, Kyoto, JP;
Inventors:
Jun Yamashita, Kyoto, JP;
Hideki Uosaki, Kyoto, JP;
Assignee:
KYOTO UNIVERSITY, Kyoto, JP;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 5/077 (2010.01); C12N 5/0775 (2010.01); G01N 33/50 (2006.01);
U.S. Cl.
CPC ...
C12N 5/0657 (2013.01); C12N 2501/415 (2013.01); C12N 5/0662 (2013.01); C12N 2501/70 (2013.01); C12N 2501/999 (2013.01); C12N 2503/02 (2013.01); G01N 33/5061 (2013.01);
Abstract
A method for proliferating cardiomyocytes and/or cardiac progenitor cells is disclosed. The proliferation method includes contact with at least one compound such as a GSK3β inhibitor, ERK dephosphorylation inhibitor, Raf activator, CaMK2 inhibitor and p38 inhibitor. The cardiomyocyte and the cardiac progenitor cell may be a human cardiomyocyte or human cardiac progenitor cell and may be obtained from differentiation of induced pluripotent stem cells.