The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 07, 2015
Filed:
Oct. 01, 2008
Timor Baasov, Haifa, IL;
Tamar Ben-yosef, Haifa, IL;
Igor Nudelman, Haifa, IL;
Annie Rebibo-sabbah, Haifa, IL;
Dalia Shallom-shezifi, Haifa, IL;
Mariana Hainrichson, Kiryat-Haim, IL;
Timor Baasov, Haifa, IL;
Tamar Ben-Yosef, Haifa, IL;
Igor Nudelman, Haifa, IL;
Annie Rebibo-Sabbah, Haifa, IL;
Dalia Shallom-Shezifi, Haifa, IL;
Mariana Hainrichson, Kiryat-Haim, IL;
Abstract
A new class of paromomycin-derived aminoglycosides, which exhibit efficient stop-codon mutation suppression activity, low toxicity and high selectivity towards eukaryotic cells are provided. Also provided are chemical and chemo-enzymatic processes of preparing these paromomycin-derived aminoglycosides and intermediates thereof, as well as pharmaceutical compositions containing the same, and uses thereof in the treatment of genetic disorders.