The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 07, 2015

Filed:

Apr. 20, 2012
Applicants:

Scott B. Hoyt, Hoboken, NJ (US);

Whitney Lane Petrilli, Jersey City, NJ (US);

Clare London, Chatham, NJ (US);

Yusheng Xiong, Plainsboro, NJ (US);

Jerry Andrew Taylor, Trenton, NJ (US);

Amjad Ali, Freehold, NJ (US);

Michael Man-chu Lo, Edison, NJ (US);

Timothy J. Henderson, Edison, NJ (US);

Qingzhong HU, Saarbrücken, DE;

Rolf Hartmann, Saarbrücken, DE;

Lina Yin, Saarbrücken, DE;

Ralf Heim, Wiesbaden, DE;

Emmanuel Bey, Forbach, DE;

Rohit Saxena, Uttar Pradesh, IN;

Swapan Kumar Samanta, Bangalore, IN;

Bheemashankar A. Kulkarni, Bangalore, IN;

Inventors:

Scott B. Hoyt, Hoboken, NJ (US);

Whitney Lane Petrilli, Jersey City, NJ (US);

Clare London, Chatham, NJ (US);

Yusheng Xiong, Plainsboro, NJ (US);

Jerry Andrew Taylor, Trenton, NJ (US);

Amjad Ali, Freehold, NJ (US);

Michael Man-Chu Lo, Edison, NJ (US);

Timothy J. Henderson, Edison, NJ (US);

Qingzhong Hu, Saarbrücken, DE;

Rolf Hartmann, Saarbrücken, DE;

Lina Yin, Saarbrücken, DE;

Ralf Heim, Wiesbaden, DE;

Emmanuel Bey, Forbach, DE;

Rohit Saxena, Uttar Pradesh, IN;

Swapan Kumar Samanta, Bangalore, IN;

Bheemashankar A. Kulkarni, Bangalore, IN;

Assignees:

ElexoPharm GmbH, Saarbrucken, DE;

Merck Sharp & Dohme Corp., Rahway, NJ (US);

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 471/04 (2006.01); C07D 487/04 (2006.01); C07D 519/00 (2006.01); A61K 31/41 (2006.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
C07D 487/04 (2013.01); A61K 31/41 (2013.01); A61K 45/06 (2013.01); C07D 471/04 (2013.01); C07D 519/00 (2013.01);
Abstract

This invention relates to tricyclic triazole analogs of the formula I or their pharmaceutically acceptable salts, wherein the variable are defined herein. The inventive compounds selectively inhibit aldosterone synthetase. This invention also provides for pharmaceutical compositions comprising the compounds of Formula I or their salts as well as to methods for the treatment, amelioration or prevention of conditions that could be treated by inhibiting aldosterone synthetase.


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