The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 07, 2015

Filed:

Feb. 17, 2011
Applicants:

Carmen M. Baldino, Woburn, MA (US);

Justin L. Caserta, Billerica, MA (US);

Chee-seng Lee, Somerville, MA (US);

Robert B. Nicewonger, Tyngsboro, MA (US);

Inventors:

Carmen M. Baldino, Woburn, MA (US);

Justin L. Caserta, Billerica, MA (US);

Chee-Seng Lee, Somerville, MA (US);

Robert B. Nicewonger, Tyngsboro, MA (US);

Assignee:

Jasco Pharmaceuticals, LLC, Woburn, MA (US);

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/506 (2006.01); A61K 31/497 (2006.01); A61K 31/5377 (2006.01); A61K 31/551 (2006.01); C07D 403/06 (2006.01); C07D 403/14 (2006.01); C07D 401/14 (2006.01); C07D 413/14 (2006.01); C07D 409/14 (2006.01); C07D 405/14 (2006.01);
U.S. Cl.
CPC ...
C07D 401/14 (2013.01); C07D 403/14 (2013.01); C07D 405/14 (2013.01); C07D 413/14 (2013.01);
Abstract

Disclosed are compounds, pharmaceutical compositions containing those compounds, and uses of the compounds and compositions as modulators of casein kinase 1 (e.g., CK1γ), the TGFβ pathway and/or the Wnt pathway. Uses are also disclosed for the treatment or prevention of a range of therapeutic indications due at least in part to aberrant physiological activity of casein kinase 1 (e.g., CK1γ), the TGFβ pathway and/or the Wnt pathway.


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