The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 9073887 B1

PDF
Full Text
Expired
Date of Patent:
Jul. 07, 2015

Filed:

Nov. 12, 2012
Applicant:

Council of Scientific & Industrial Research, New Delhi, IN;

Inventors:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 307/00 (2006.01); C07D 307/88 (2006.01); C07B 53/00 (2006.01); C07D 307/92 (2006.01); C07D 493/04 (2006.01);
U.S. Cl.
CPC ...
C07D 307/88 (2013.01); C07B 53/00 (2013.01); C07D 307/92 (2013.01); C07D 493/04 (2013.01);
Abstract

The present invention discloses single step, highly enantioselective catalytic oxidative cyclization process for the synthesis of 3-substituted chiral phthalides. In particular, the invention discloses asymmetric synthesis of chiral phthalides via synergetic nitrile accelerated oxidative cyclization of o-cyano substituted aryl alkenes in high yield and enantiomeric excess (ee) in short reaction time. Also, disclosed herein is 'one-pot' asymmetric synthesis of biologically important natural compounds having 3-substituted chiral phthalide structural framework in the molecule.


Find Patent Forward Citations

Reddy, Rekula. (2015). Single step enantioselective process for the preparation of 3-substituted chiral phthalides (U.S. Patent No. 9073887). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/9073887

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