The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 07, 2015
Filed:
Jun. 03, 2011
William Gerwick, La Jolla, CA (US);
Lena Gerwick, La Jolla, CA (US);
Hyuakjae Choi, San Diego, CA (US);
Francisco Villa, La Jolla, CA (US);
Jennifer Smith, San Diego, CA (US);
David C Rowley, Wakefield, RI (US);
William Gerwick, La Jolla, CA (US);
Lena Gerwick, La Jolla, CA (US);
Hyuakjae Choi, San Diego, CA (US);
Francisco Villa, La Jolla, CA (US);
Jennifer Smith, San Diego, CA (US);
David C Rowley, Wakefield, RI (US);
The Regents of the University of California, Oakland, CA (US);
University of Rhode Island Research Foundation, Kingston, RI (US);
Abstract
The invention provides novel compositions based on a structure designated as 'Honaucin A', including Honaucin A variants and analogs, and pharmaceutical compositions, liposomes and nanoparticles comprising them, and methods of making and using them. In one embodiment, these Honaucin A compounds, and variants and analogs thereof are used to ameliorate (including to treat or prevent) inflammation. In one embodiment, these Honaucin A compounds, and variants and analogs thereof are used to ameliorate (including to treat or prevent) inflammation. In one embodiment, these Honaucin A compounds, and variants and analogs thereof are used as bacterial quorumsensing inhibitors. Accordingly, in alternative embodiments the compositions of the invention are used as anti-bacterial agents.