The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 07, 2015

Filed:

Sep. 05, 2012
Applicant:

Paul Gillespie, Westfield, NJ (US);

Inventor:

Paul Gillespie, Westfield, NJ (US);

Assignee:

HOFFMANN-LA ROCHE INC., Nutley, NJ (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/426 (2006.01); A61K 31/496 (2006.01); A61K 31/506 (2006.01); C07D 417/10 (2006.01); A61K 31/4439 (2006.01); C07D 417/04 (2006.01); C07D 277/30 (2006.01); A61K 31/427 (2006.01); A61K 31/5377 (2006.01); A61K 31/454 (2006.01); C07D 277/34 (2006.01); C07D 417/08 (2006.01); C07D 417/12 (2006.01); C07D 277/38 (2006.01);
U.S. Cl.
CPC ...
C07D 277/34 (2013.01); C07D 417/04 (2013.01); C07D 417/08 (2013.01); C07D 417/12 (2013.01); C07D 277/38 (2013.01);
Abstract

There are disclosed are compounds of the formula: wherein R1 and R2 are as disclosed herein,which are eIF4E inhibitors useful in the treatment of cancers. Also disclosed are compositions comprising the compounds, as well as methods of treating cancer using the compounds.


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