The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 07, 2015
Filed:
Jul. 01, 2011
Applicants:
Alexandre Vasilievich Ivachtchenko, Encinitas, CA (US);
Oleg Dmitrievich Mitkin, Moscow, RU;
Inventors:
Alexandre Vasilievich Ivachtchenko, Encinitas, CA (US);
Oleg Dmitrievich Mitkin, Moscow, RU;
Assignee:
Other;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/505 (2006.01); C07D 233/86 (2006.01); C07D 233/72 (2006.01); C07D 239/10 (2006.01); C07D 239/22 (2006.01); C07D 249/12 (2006.01); C07D 471/10 (2006.01); C07D 491/107 (2006.01); A61K 9/00 (2006.01); A61K 9/20 (2006.01); A61K 9/48 (2006.01);
U.S. Cl.
CPC ...
C07D 233/86 (2013.01); C07D 233/72 (2013.01); C07D 239/10 (2013.01); C07D 239/22 (2013.01); C07D 249/12 (2013.01); C07D 471/10 (2013.01); C07D 491/107 (2013.01); A61K 9/0019 (2013.01); A61K 9/2018 (2013.01); A61K 9/2059 (2013.01); A61K 9/2095 (2013.01); A61K 9/4858 (2013.01);
Abstract
The invention relates to novel N,N'-disubstituted 2-thioxo-7-oxa-1,3-diaza-spiro[4.4]nonan-4-one-androgen receptor (AR) antagonists, an anticancer agent, a pharmaceutical composition, a medicament, and a method for treating prostate cancer. 4-[3-(4-Cyano-3-trifluoromethyl-phenyl)-4-oxo-2-thioxo-7-oxa-1,3-diaza-spiro[4.4]non-1-yl]-2-fluoro-benzamide of general formula 1 and enantiomer thereof