The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 07, 2015

Filed:

Apr. 16, 2009
Applicants:

Martial Ruat, Orsay, FR;

Hélène Faure, Gif-sur-Yvette, FR;

Elisabeth Traiffort, Paris, FR;

Angèle Schoenfelder, Lampertheim, FR;

André Mann, Ostwald, FR;

Maurizio Taddei, Monteriggioni, IT;

Antonio Solinas, Siena, IT;

Fabrizio Manetti, Castelnuovo Berardenga, IT;

Inventors:

Martial Ruat, Orsay, FR;

Hélène Faure, Gif-sur-Yvette, FR;

Elisabeth Traiffort, Paris, FR;

Angèle Schoenfelder, Lampertheim, FR;

André Mann, Ostwald, FR;

Maurizio Taddei, Monteriggioni, IT;

Antonio Solinas, Siena, IT;

Fabrizio Manetti, Castelnuovo Berardenga, IT;

Assignees:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07C 275/54 (2006.01); C07C 335/26 (2006.01); C07D 213/81 (2006.01); C07D 209/08 (2006.01); C07D 209/14 (2006.01); C07D 235/14 (2006.01); C07D 307/68 (2006.01); C07D 317/68 (2006.01); C07D 319/18 (2006.01); C07D 333/38 (2006.01); C07D 471/04 (2006.01); C07D 513/04 (2006.01); C07D 235/18 (2006.01); C07C 335/08 (2006.01);
U.S. Cl.
CPC ...
C07C 335/26 (2013.01); C07D 235/18 (2013.01); C07C 335/08 (2013.01); C07C 275/54 (2013.01); C07C 2101/14 (2013.01); C07D 209/08 (2013.01); C07D 209/14 (2013.01); C07D 213/81 (2013.01); C07D 235/14 (2013.01); C07D 307/68 (2013.01); C07D 317/68 (2013.01); C07D 319/18 (2013.01); C07D 333/38 (2013.01); C07D 471/04 (2013.01); C07D 513/04 (2013.01);
Abstract

The present invention relates to the use of acylthiourea or acylurea derivatives for the treatment of pathologies involving a tissue dysfunction associated with a deregulation of the Hedgehog protein signalling pathway, and also to novel acylthiourea or acylurea derivatives as such, to their use as a medicinal product, and to pharmaceutical compositions containing them.


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