The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 07, 2015

Filed:

Jul. 21, 2011
Applicants:

Young Eun Woo, Daejeon, KR;

Jong Soo Lee, Seongnam-si, KR;

Ling Ai Shen, Seoul, KR;

Dae Jin Kim, Hwaseong-si, KR;

Sung Youb Jung, Suwon-si, KR;

IN Young Choi, Yongin-si, KR;

SE Chang Kwon, Seoul, KR;

Inventors:

Young Eun Woo, Daejeon, KR;

Jong Soo Lee, Seongnam-si, KR;

Ling Ai Shen, Seoul, KR;

Dae Jin Kim, Hwaseong-si, KR;

Sung Youb Jung, Suwon-si, KR;

In Young Choi, Yongin-si, KR;

Se Chang Kwon, Seoul, KR;

Assignee:

HANMI SCIENCE CO., LTD, Hwaseong-si, KR;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/385 (2006.01); A61K 39/00 (2006.01); A61K 38/26 (2006.01); A61K 38/00 (2006.01); A61K 38/22 (2006.01); A61K 47/48 (2006.01); A61K 31/4164 (2006.01); A61K 45/06 (2006.01); C07K 14/605 (2006.01);
U.S. Cl.
CPC ...
A61K 47/48415 (2013.01); A61K 31/4164 (2013.01); A61K 38/26 (2013.01); A61K 45/06 (2013.01); A61K 47/48369 (2013.01); C07K 14/605 (2013.01); A61K 47/48692 (2013.01);
Abstract

Disclosed is a novel long-acting glucagon conjugate in which glucagon or its derivative is covalently linked to a polymer carrier via a non-peptide linker, and a pharmaceutical composition comprising the same as an effective ingredient useful for the prevention and treatment of obesity. Since the long-acting glucagon conjugate of the present invention shows improved in vivo durability and stability, when used in combination with an anti-obesity drug, it is possible to induce synergistic effects on the loss of body weight and decrease in food intake without causing any side-effects such as fluctuation in blood glucose level. Accordingly, the long-acting peptide conjugate of the present invention is very effective for the prevention and treatment of obesity.


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