The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 07, 2015

Filed:

Jun. 19, 2013
Applicants:

Universite DE LA Mediterranee Aix-marseille Ii, Marseilles, FR;

Association Francaise Contre Les Myopathies (Afm), Paris Cedex, FR;

Assistance Publique Hopitaux DE Marseille, Marseilles Cedex, FR;

Universidad DE Oviedo, Oviedo, ES;

Inventors:

Nicolas Levy, Marseilles, FR;

Pierre Cau, Puyricard, FR;

Carlos Lopez-Otin, Oviedo, ES;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/66 (2006.01); A61K 31/21 (2006.01); A61K 31/22 (2006.01); A61K 31/675 (2006.01); A61K 31/663 (2006.01); A61K 31/215 (2006.01);
U.S. Cl.
CPC ...
A61K 31/675 (2013.01); A61K 31/22 (2013.01); A61K 31/663 (2013.01); A61K 31/215 (2013.01);
Abstract

The invention relates to the use of a hydroxymethylglutaryl-coenzyme A (HMG-CoA) reductase inhibitor and of a farnesyl-pyrophosphate synthase inhibitor, or of one of their associated physiologically acceptable salts, in the preparation of a composition, particularly a pharmaceutical composition, for use in the treatment of human or animal, pathological or nonpathological situations related to the accumulation and/or the persistence of prenylated proteins in cells, such as during progeria (Hutchinson-Gilford syndrome), restrictive dermopathy or physiological ageing.


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