The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 07, 2015
Filed:
Jul. 01, 2011
Applicant:
Gregory J. Bix, College Station, TX (US);
Inventor:
Gregory J. Bix, College Station, TX (US);
Assignee:
THE TEXAS A&M UNIVERSITY SYSTEM, College Station, TX (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 1/00 (2006.01); A61K 38/02 (2006.01); A61K 31/727 (2006.01); A61K 38/20 (2006.01); A61K 38/17 (2006.01); A61K 45/06 (2006.01); C07K 16/28 (2006.01);
U.S. Cl.
CPC ...
A61K 38/2006 (2013.01); A61K 31/727 (2013.01); A61K 38/177 (2013.01); A61K 45/06 (2013.01); A61K 2300/00 (2013.01); C07K 16/2842 (2013.01); C07K 2317/75 (2013.01); C07K 2317/76 (2013.01); C07K 2317/34 (2013.01);
Abstract
The disclosed invention relates to the use of perlecan domain V (DV) for the treatment of stroke, traumatic brain injury (TBI) or spinal cord injuries (SCI). In certain embodiments, fusion proteins of DV can be used for the treatment of stroke, TBI or SCI. DV is also referred to as endorepellin in the art. This application also provides compositions and combination therapies for the treatment of stroke, TCI and/or SCI. Another aspect of the invention provides methods of restoring motor function in subjects having neurological damage arising from a stroke, TBI or SCI.