The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 07, 2015
Filed:
May. 29, 2012
Ki Hun Park, Gyeongsangnam-do, KR;
Jung Weon Lee, Seoul, KR;
Young Bae Ryu, Gyeongsangnam-do, KR;
Hyung Won Ryu, Gyeongsangnam-do, KR;
Sin-ae Lee, Seoul, KR;
Ki Hun Park, Gyeongsangnam-do, KR;
Jung Weon Lee, Seoul, KR;
Young Bae Ryu, Gyeongsangnam-do, KR;
Hyung Won Ryu, Gyeongsangnam-do, KR;
Sin-Ae Lee, Seoul, KR;
Seoul National University Industry Foundation, Seoul, KR;
Industry-Academic Cooperation Foundation Gyeongsang National University, Gyeongsangnam-do, KR;
Abstract
The present invention relates to a method for screening an anticancer compound and an anticancer compound screened using the method, and more particularly, to a method for screening an anticancer compound, the method comprising: culturing cancer cells expressing the oncogenic protein transmembrane 4 L6 family member 5 (TM4SF5), expressed as the polypeptide of SEQ ID NO: 2, treating the cancer cells with an anticancer candidate, and determining that the anticancer candidate is an anticancer substance when the candidate exhibits antagonistic activity against tumor formation and metastasis based on several events through the molecular mechanism of TM4SF5. The present invention also relates to chalcone compounds screened to have anticancer activity using the method, and an anticancer composition comprising the compound as an effective ingredient.