The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 30, 2015
Filed:
Nov. 19, 2013
Applicant:
Trustees of Tufts College, Medford, MA (US);
Inventors:
Daniel G. Jay, Jamaica Plain, MA (US);
Brenda K. Eustace, Brookline, MA (US);
Takashi Sakurai, Tokyo, JP;
Assignee:
TRUSTEES OF TUFTS COLLEGE, Medford, MA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/574 (2006.01); A61K 31/366 (2006.01); C07K 16/30 (2006.01); A61K 39/395 (2006.01); A61K 31/395 (2006.01); A61K 47/48 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
G01N 33/574 (2013.01); G01N 33/57484 (2013.01); A61K 31/366 (2013.01); A61K 2039/505 (2013.01); C07K 16/30 (2013.01); C07K 2317/622 (2013.01); A61K 39/39558 (2013.01); C07K 2317/34 (2013.01); A61K 31/395 (2013.01); A61K 47/4823 (2013.01); A61K 47/48923 (2013.01);
Abstract
The present invention describes inhibitors of extracellular Hsp90. The inhibition of extracellular Hsp90 leads to a reduction of the invasiveness of the tumor cells. Furthermore, the invention relates to the use of molecules inhibiting extracellular Hsp90 function for the manufacture of a medicament for the treatment or prevention of invasion and/or metastatic potential of cancer cells.