The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 30, 2015
Filed:
Nov. 06, 2009
Louise C. Showe, Media, PA (US);
Michael Showe, Media, PA (US);
Andrew V. Kossenkov, Philadelphia, PA (US);
Elena Nikonova, Swarthmore, PA (US);
Louise C. Showe, Media, PA (US);
Michael Showe, Media, PA (US);
Andrew V. Kossenkov, Philadelphia, PA (US);
Elena Nikonova, Swarthmore, PA (US);
THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY, Philadelphia, PA (US);
Abstract
Methods and compositions are provided for diagnosing or detecting a condition, e.g., lung disease in a mammalian subject by use of a micro-RNA expression level or an expression level profile of multiple miRNA in the peripheral blood mononuclear cells (PBMC) of the subject which is characteristic of COPD or NSCLC. Detection of changes in expression in specific miRNA biomarkers from that of a reference sample or miRNA expression profile are correlated with non-small cell lung cancer (NSCLC) and/or COPD and permit differentiation among healthy subjects, subjects with COPD and subjects with adenocarcinoma or squamous cell carcinoma.