The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 30, 2015

Filed:

Apr. 30, 2013
Applicants:

Pola Pharma Inc., Tokyo, JP;

Nihon Nohyaku Co., Ltd., Tokyo, JP;

Inventors:

Takaaki Masuda, Kanagawa, JP;

Hideo Kaneda, Tokyo, JP;

Assignees:

POLA PHARMA INC., Tokyo, JP;

NIHON NOHYAKU CO., LTD., Tokyo, JP;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
G01N 33/15 (2006.01); C07D 409/06 (2006.01);
U.S. Cl.
CPC ...
G01N 33/15 (2013.01); C07D 409/06 (2013.01); C07B 2200/13 (2013.01);
Abstract

An object is to provide means for suppressing the formation of any isomer of luliconazole on account of any influence of, for example, the humidity and the light and improving the stability. Disclosed is a method for differential evaluating a crystal of luliconazole, comprising differential evaluating the crystal by using, as indexes, surface free energy of the crystal of luliconazole and a ratio of a polar component of the surface free energy, wherein the crystal is evaluated to be stable on condition that the surface free energy is smaller and the ratio of the polar component is lower.


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