The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 30, 2015
Filed:
Sep. 16, 2011
Applicants:
Ki Chul Hwang, Seoul, KR;
Yang Soo Jang, Seoul, KR;
Gyoon Hee Han, Gyeonggi-do, KR;
Inventors:
Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07C 311/21 (2006.01); C07D 215/36 (2006.01); C12N 5/071 (2010.01); C12N 5/077 (2010.01); A61K 31/18 (2006.01); A61K 31/47 (2006.01); C07C 311/17 (2006.01); C07C 311/20 (2006.01);
U.S. Cl.
CPC ...
C12N 5/0655 (2013.01); A61K 31/18 (2013.01); A61K 31/47 (2013.01); C12N 2501/999 (2013.01); C12N 2501/727 (2013.01); C07C 311/21 (2013.01); C07D 215/36 (2013.01); C07C 311/17 (2013.01); C07C 311/20 (2013.01); C07C 2101/14 (2013.01); C12N 2506/1353 (2013.01);
Abstract
Use of a compound of Formula 1 for inducing differentiation of mesenchymal stem cells to chondrocytes, and a pharmaceutical composition for treating a cartilage disease, which includes chondrocytes in which differentiation from mesenchymal stem cells is induced by the compound of Formula 1, are provided. Differentiation of the mesenchymal stem cells treated with the compound of Formula 1 to chondrocytes is specifically induced, and thus the compound can be used to effectively treat a cartilage disease such as arthritis, cartilage damage, and a cartilage defect.