The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 30, 2015
Filed:
Oct. 19, 2010
Sung Wuk Kim, Seongnam-si, KR;
Sung Soo Jun, Seongnam-si, KR;
Seung Kook Park, Seoul, KR;
Song Young Kim, Suwon-si, KR;
Eun Sun Kim, Suwon-si, KR;
Jae Kap Jeong, Suwon-si, KR;
Ha NA Kim, Suwon-si, KR;
Yeon Jung Song, Yongin-si, KR;
Sung Wuk Kim, Seongnam-si, KR;
Sung Soo Jun, Seongnam-si, KR;
Seung Kook Park, Seoul, KR;
Song Young Kim, Suwon-si, KR;
Eun Sun Kim, Suwon-si, KR;
Jae Kap Jeong, Suwon-si, KR;
Ha Na Kim, Suwon-si, KR;
Yeon Jung Song, Yongin-si, KR;
HANALL BIOPHARMA CO., LTD., Daejeon, KR;
Abstract
The present invention relates to a modified human tumor necrosis factor receptor-1 polypeptide to be coupled to a tumor necrosis factor in vivo or ex vivo, or to a fragment thereof. The modified human tumor necrosis factor receptor-1 polypeptide or the fragment thereof according to the present invention exhibit improved resistance against in vivo protease activity, and thus exhibit improved bioavailability and an improved absorption rate.