The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 30, 2015
Filed:
Nov. 19, 2013
Emd Millipore Corporation, Billerica, MA (US);
Kwok-Shun Cheng, Nashua, NH (US);
Senthilkumar Ramaswamy, Nashua, NH (US);
Chen Wang, Acton, MA (US);
Nanying Bian, Lexington, MA (US);
Brian Gagnon, Billerica, MA (US);
Joaquin A. Umana, Reading, MA (US);
Dennis Aquino, Chelmsford, MA (US);
Neil Soice, Groton, MA (US);
Andrew Lyddiatt, Co Durham, GB;
EMD Millipore Corporation, Billerica, MA (US);
Abstract
The present invention relates to an asymmetric chromatography media suitable for separations applications, particularly as packed bed, fluidized bed or magnetized bed chromatography media. In certain embodiments, the asymmetric chromatography media comprises asymmetric particles, preferably beads, having at least two distinct, controlled pore size distributions. Preferably one of the distinct pore size distributions is in an internal region of the particle, and the other is in an external region or coating on the particle. These distinct pore size distributions can be modified with uniform or alternatively unique functional groups or mixtures of functional groups. The present invention allows for the control over pore size distribution within an asymmetric porous particle by providing a distinct internal region, preferably in the form of a bead, and a distinct external region, preferably in the form of a coating on the bead.