The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 30, 2015

Filed:

Jan. 18, 2012
Applicants:

Peter R. Guzzo, Niskayuna, NY (US);

Alan J. Henderson, Fishers, IN (US);

Matthew Isherwood, Delmar, NY (US);

Chong Yew Lee, Kuala Lumpur, MY;

Animesh Ghosh, Singapore, SG;

He Zhao, Madison, CT (US);

Inventors:

Peter R. Guzzo, Niskayuna, NY (US);

Alan J. Henderson, Fishers, IN (US);

Matthew Isherwood, Delmar, NY (US);

Chong Yew Lee, Kuala Lumpur, MY;

Animesh Ghosh, Singapore, SG;

He Zhao, Madison, CT (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 491/048 (2006.01); C07D 307/91 (2006.01); C07D 491/18 (2006.01); C07D 491/08 (2006.01);
U.S. Cl.
CPC ...
C07D 491/048 (2013.01); C07D 307/91 (2013.01); C07D 491/18 (2013.01); C07D 491/08 (2013.01);
Abstract

The present invention relates to benzofuro[3,2-c]pyridine and azepine analogs as serotonin sub-type 6 (5-HT) modulators, pharmaceutical compositions including these compounds, methods of preparation, and use thereof. These compounds are useful in the treatment of central nervous system disorders including obesity, metabolic syndrome, cognition, schizophrenia, attention deficit hyperactivity disorder, bipolar disorder, rare and orphan diseases, and sleep disorders. The subject compounds have the structure of formula (I) with the substituents being described herein.


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