The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 30, 2015

Filed:

Feb. 28, 2014
Applicant:

Otsuka Pharmaceutical Co., Ltd., Tokyo, JP;

Inventors:

Mamuti Abudusaimi, Shanghai, CN;

Fangguo Ye, Shanghai, CN;

Jiangqin Sun, Shanghai, CN;

Hisashi Miyamoto, Osaka, JP;

Jay-Fei Cheng, Shanghai, CN;

Daisuke Oka, Osaka, JP;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 215/38 (2006.01); C07D 215/56 (2006.01); C07D 401/04 (2006.01); C07D 401/14 (2006.01); C07D 405/04 (2006.01); C07D 417/04 (2006.01); C07D 471/04 (2006.01); C07D 498/06 (2006.01); C07D 413/14 (2006.01); C07D 401/10 (2006.01); C07D 409/04 (2006.01); C07D 409/14 (2006.01); C07D 413/04 (2006.01); C07D 487/04 (2006.01); C07D 498/04 (2006.01);
U.S. Cl.
CPC ...
C07D 215/56 (2013.01); C07D 401/04 (2013.01); C07D 401/14 (2013.01); C07D 405/04 (2013.01); C07D 417/04 (2013.01); C07D 471/04 (2013.01); C07D 498/06 (2013.01); C07D 413/14 (2013.01); C07D 401/10 (2013.01); C07D 409/04 (2013.01); C07D 409/14 (2013.01); C07D 413/04 (2013.01); C07D 487/04 (2013.01); C07D 498/04 (2013.01);
Abstract

The present invention provides a compound represented by the formula (I) wherein X is a hydrogen atom or a fluorine atom; R is a hydrogen atom or alkyl; Ris (1) cyclopropyl optionally substituted by 1 to 3 halogen atoms or (2) phenyl optionally substituted by 1 to 3 halogen atoms; Ris alkyl, alkoxy, haloalkoxy, a halogen atom, cyano, etc.; and Ris 7-oxo-7,8-dihydro-1,8-naphthyridinyl, 3-pyridyl, etc., or a salt thereof. The compound of the present invention has excellent antimicrobial activity againstand is useful for the prevention or treatment of intestinal infection such as-associated diarrhea.


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