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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 9067871 B1

PDFFull Text
Date of Patent:
Jun. 30, 2015

Filed:

Sep. 19, 2013

Aminotetraline derivatives, pharmaceutical compositions containing them, and their use in therapy

Applicants:

Abbvie Deutschland Gmbh & CO KG, Wiesbaden, DE;

Abbott Laboratories, Abbott Park, IL (US);

Inventors:

Wilhelm Amberg, Wiesbaden, DE;

Michael Ochse, Wiesbaden, DE;

Udo Lange, Wiesbaden, DE;

Andreas Kling, Wiesbaden, DE;

Berthold Behl, Wiesbaden, DE;

Wilfried Hornberger, Wiesbaden, DE;

Mario Mezler, Wiesbaden, DE;

Charles W. Hutchins, Green Oaks, IL (US);

Assignees:

AbbVie Deutschland GmbH & Co. KG, Wiesbaden, DE;

AbbVie Inc., North Chicago, IL (US);

Attorneys:

Lisa V. Mueller

Michael Best & Friedrich LLP

Primary Examiner:

Kamal Saeed

Assistant Examiner:

Janet L Coppins

Int. Cl.
CPC ...
A61K 31/16 (2006.01); C07C 215/70 (2006.01); C07C 311/05 (2006.01); C07C 215/64 (2006.01); C07C 217/74 (2006.01); C07C 233/18 (2006.01); C07C 233/19 (2006.01); C07C 233/69 (2006.01); C07C 255/58 (2006.01); C07C 271/24 (2006.01); C07C 307/06 (2006.01); C07C 309/65 (2006.01); C07C 311/07 (2006.01); C07C 311/09 (2006.01); C07C 311/10 (2006.01); C07C 311/14 (2006.01); C07C 311/17 (2006.01); C07C 311/18 (2006.01); C07C 311/20 (2006.01); C07C 311/24 (2006.01); C07C 317/18 (2006.01); C07C 317/28 (2006.01); C07D 205/04 (2006.01); C07D 207/10 (2006.01); C07D 207/12 (2006.01); C07D 207/27 (2006.01); C07D 207/36 (2006.01); C07D 207/48 (2006.01); C07D 213/71 (2006.01); C07D 231/18 (2006.01); C07D 233/84 (2006.01); C07D 249/12 (2006.01); C07D 261/08 (2006.01); C07D 275/02 (2006.01); C07D 295/096 (2006.01); C07D 305/08 (2006.01); C07D 333/34 (2006.01); C07D 403/12 (2006.01); C07F 7/08 (2006.01); C07D 401/12 (2006.01); C07D 409/12 (2006.01);
U.S. Cl.
CPC ...
C07C 311/05 (2013.01); C07C 215/64 (2013.01); C07C 217/74 (2013.01); C07C 233/18 (2013.01); C07C 233/19 (2013.01); C07C 233/69 (2013.01); C07C 255/58 (2013.01); C07C 271/24 (2013.01); C07C 307/06 (2013.01); C07C 309/65 (2013.01); C07C 311/07 (2013.01); C07C 311/09 (2013.01); C07C 311/10 (2013.01); C07C 311/14 (2013.01); C07C 311/17 (2013.01); C07C 311/18 (2013.01); C07C 311/20 (2013.01); C07C 311/24 (2013.01); C07C 317/18 (2013.01); C07C 317/28 (2013.01); C07C 2101/02 (2013.01); C07C 2101/04 (2013.01); C07C 2102/10 (2013.01); C07D 205/04 (2013.01); C07D 207/10 (2013.01); C07D 207/12 (2013.01); C07D 207/27 (2013.01); C07D 207/36 (2013.01); C07D 207/48 (2013.01); C07D 213/71 (2013.01); C07D 231/18 (2013.01); C07D 233/84 (2013.01); C07D 249/12 (2013.01); C07D 261/08 (2013.01); C07D 275/02 (2013.01); C07D 295/096 (2013.01); C07D 305/08 (2013.01); C07D 333/34 (2013.01); C07D 403/12 (2013.01); C07F 7/0818 (2013.01); C07D 401/12 (2013.01); C07D 409/12 (2013.01);
Abstract

The present invention relates to aminotetraline derivatives of the formula (I) or a physiologically tolerated salt thereof. The invention relates to pharmaceutical compositions comprising such aminotetraline derivatives, and the use of such aminotetraline derivatives for therapeutic purposes. The aminotetraline derivatives are GlyT1 inhibitors.

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