The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 30, 2015
Filed:
Jul. 25, 2012
Applicants:
Luca Carcone, Cervaro, IT;
Domenico Magrone, Verona, IT;
Giuseppe Barreca, Montevecchia, IT;
Marcello Rasparini, Cura Carpignano, IT;
Huang Liming, Haiyou Town, CN;
Inventors:
Luca Carcone, Cervaro, IT;
Domenico Magrone, Verona, IT;
Giuseppe Barreca, Montevecchia, IT;
Marcello Rasparini, Cura Carpignano, IT;
Huang Liming, Haiyou Town, CN;
Assignee:
Chemo Iberica, S.A., Barcelona, ES;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07C 231/02 (2006.01); C07C 231/14 (2006.01); C07C 231/12 (2006.01);
U.S. Cl.
CPC ...
C07C 231/02 (2013.01); C07C 231/14 (2013.01); C07C 231/12 (2013.01);
Abstract
It is described a process for the opening of lactone or lactam rings useful in the synthesis of pharmaceutically active compounds and the intermediates thereof, particularly Aliskiren. It has found that by selecting a type of solvent it is possible to obtain excellent yields and high optical and chemical purity of the isolated products.