The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 30, 2015
Filed:
Feb. 01, 2013
Methods and pharmaceutical compositions for the treatment of cardiomyopathy due to friedreich ataxia
Institut National DE LA Sante ET DE LA Recherche Medicale (Inserm), Paris, FR;
Cnrs (Centre National DE LA Recherche Scientifique), Paris, FR;
Universite DE Strasbourg, Strasbourg, FR;
Cornell University, Ithaca, NY (US);
Universite Paris-sud Xi, Orsay Cedex, FR;
Assistance Publique-hopitaux DE Paris (Aphp), Paris, FR;
Helene Monique Puccio, Illkirch, FR;
Patrick Aubourg, Le Kremlin Bicetre, FR;
Ronald G. Crystal, New York, NY (US);
Pierre Bougneres, Le Kremlin Bicetre, FR;
Institut National de la Sante et de la Recherche Medicale (INSERM), Paris, FR;
CNRS (Centre National de la Recherche Scientifique), Paris, FR;
Universite de Strasbourg, Strasbourg, FR;
Cornell University, Itahca, NY (US);
Universite Paris-Sud XI, Orsay Cedex, FR;
Assistance Publique-Hopitaux de Paris (APHP), Paris, FR;
Abstract
A method for preventing or treating cardiomyopathy due to energy failure in a subject in need thereof is provided. The method comprises administering to the subject a therapeutically effective amount of a vector which comprises a nucleic acid sequence encoding a gene that can reverse energy failure. An exemplary cardiomyopathy is that which is associated with Friedreich ataxia and an exemplary nucleic acid sequence comprises a nucleic acid that encodes frataxin (FXN).