The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 30, 2015
Filed:
Aug. 22, 2007
Yuling Liu, Beijing, CN;
Zhufang Shen, Beijing, CN;
Zhen Chen, Beijing, CN;
Renyun Wang, Beijing, CN;
Xuejun Xia, Beijing, CN;
Yueteng Chen, Beijing, CN;
Quan Liu, Beijing, CN;
Sujuan Sun, Beijing, CN;
Mingzhi Xie, Beijing, CN;
Yuling Liu, Beijing, CN;
Zhufang Shen, Beijing, CN;
Zhen Chen, Beijing, CN;
Renyun Wang, Beijing, CN;
Xuejun Xia, Beijing, CN;
Yueteng Chen, Beijing, CN;
Quan Liu, Beijing, CN;
Sujuan Sun, Beijing, CN;
Mingzhi Xie, Beijing, CN;
Abstract
The present invention relates to an effective fraction of alkaloids and the effective fraction is prepared from mulberry twig and its active ingredients are a composition of alkaloids. Determined by HPLC, the percentage of the total alkaloids are 50% or more by weight in the effective fraction and the percentage of the compound 1-deoxynojirimycin is 30% or more by weight in the total alkaloids. The effective fraction of the invention is prepared as the following steps: the mulberry twig is extracted by solvents, and the extract is precipitated by alcohol precipitation or flocculation to remove the impurities, and then concentrated, purified by resin chromatography. The present invention also relates to a pharmaceutical composition containing the said effective fraction of alkaloids and to the use of the effective fraction of alkaloids according to claim-in preparing hypoglycemic agents.