The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 30, 2015

Filed:

Aug. 06, 2010
Applicants:

Yiqiao HU, Jiangsu, CN;

Jinhui Wu, Jiangsu, CN;

Dawei Ding, Jiangsu, CN;

Guangming Gong, Jiangsu, CN;

Xiaolei Tang, Jiangsu, CN;

Chunhui Tong, Jiangsu, CN;

Yan Zhu, Jiangsu, CN;

Shaoling LI, Sunnyvale, CA (US);

Inventors:

Yiqiao Hu, Jiangsu, CN;

Jinhui Wu, Jiangsu, CN;

Dawei Ding, Jiangsu, CN;

Guangming Gong, Jiangsu, CN;

Xiaolei Tang, Jiangsu, CN;

Chunhui Tong, Jiangsu, CN;

Yan Zhu, Jiangsu, CN;

Shaoling Li, Sunnyvale, CA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 9/16 (2006.01); A61K 9/28 (2006.01); B01J 13/00 (2006.01); B05D 3/00 (2006.01); A61K 9/19 (2006.01); A61K 9/51 (2006.01);
U.S. Cl.
CPC ...
A61K 9/19 (2013.01); A61K 9/5138 (2013.01); A61K 9/5192 (2013.01);
Abstract

The present invention provides preparation methods of protein nanoparticles for in vivo delivery of pharmacologically active agents, wherein said methods are to encase pharmaceutically active agents into proteins or peptides to form nanoparticles by unfolding the protein, and subsequently refolding or assembling the protein to produce a pharmacologically active agent encased within a protein nanoparticle.


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