The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 23, 2015

Filed:

Feb. 23, 2004
Applicant:

Michael Paul Brown, St. Georges, AU;

Inventor:

Michael Paul Brown, St. Georges, AU;

Assignee:

Medvet Science Pty Ltd, Stepney, AU;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/395 (2006.01); G01N 33/68 (2006.01); A61K 47/48 (2006.01); A61K 51/10 (2006.01); C07K 16/18 (2006.01); G01N 33/50 (2006.01); C07K 16/28 (2006.01);
U.S. Cl.
CPC ...
G01N 33/6875 (2013.01); A61K 47/48538 (2013.01); A61K 51/1018 (2013.01); C07K 16/18 (2013.01); G01N 33/5017 (2013.01); G01N 2510/00 (2013.01);
Abstract

The present invention relates generally to a method for detecting an aberrant cell, and more particularly an apoptotic cell, in a subject or in a biological sample from said subject, and agents useful for same. The presence of the aberrant cell or group of aberrant cells provides an indication of a particular disease or condition or a propensity for development of a disease or condition. More particularly, the present invention contemplates a method for detecting an apoptotic cell by detecting the presence of extranuclear nuclear molecules, in particular La, or a relative increase in extranuclear nuclear molecule levels. The present invention further provides a method for diagnosing or monitoring conditions characterized by aberrant, unwanted or otherwise inappropriate cellular apoptosis in a subject or in a biological sample from said subject by screening for up-regulation of extranuclear nuclear molecule levels in a cell or group of cells. The present invention provides diagnostic agents useful for detecting these molecules. Such diagnostic agents include immunointeractive molecules, such as antibodies.


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