The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 23, 2015

Filed:

Apr. 26, 2013
Applicant:

Xrpro Sciences, Inc., Los Alamos, NM (US);

Inventors:

Benjamin P. Warner, Los Alamos, NM (US);

Rebecca L. E. Miller, Los Alamos, NM (US);

Lori J. Peterson, Los Alamos, NM (US);

Jennifer A. Berger, White Rock, NM (US);

Eva R. Birnbaum, Los Alamos, NM (US);

Assignee:

Caldera Pharmaceuticals, Inc., Los Alamos, NM (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12Q 1/02 (2006.01); G01N 21/76 (2006.01); G01N 23/223 (2006.01); G01N 33/50 (2006.01); G01N 33/68 (2006.01);
U.S. Cl.
CPC ...
G01N 33/6872 (2013.01); G01N 23/223 (2013.01); G01N 33/502 (2013.01); G01N 2223/076 (2013.01);
Abstract

The present invention comprises a method for measuring the transport of analytes through a cell. The method comprises the steps of providing one or more cells containing at least 10 picograms of an analyte within a volume defined by the area of an x-ray excitation beam and a depth of live times the 1/e attenuation, depth for at least one characteristic x-ray signal of the analyte as attenuated by water. The method further comprises the step of removing at least a of portion of the analyte from the cells. The method also comprises the steps of exciting at least a portion of the analyte that has been removed from the cells with an x-ray beam; and using an x-ray detector to measure x-ray fluorescence.


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