The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 23, 2015
Filed:
Mar. 22, 2012
Applicants:
Michael D. Henry, Iowa City, IA (US);
J. Matthew Barnes, Iowa City, IA (US);
Inventors:
Michael D. Henry, Iowa City, IA (US);
J. Matthew Barnes, Iowa City, IA (US);
Assignee:
University of Iowa Research Foundation, Iowa City, IA (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N 5/00 (2006.01); C12N 5/02 (2006.01); G01N 33/487 (2006.01); G01N 33/50 (2006.01); G01N 33/574 (2006.01); C12N 5/09 (2010.01);
U.S. Cl.
CPC ...
G01N 33/487 (2013.01); G01N 33/5026 (2013.01); G01N 33/5044 (2013.01); G01N 33/5091 (2013.01); G01N 33/574 (2013.01); C12N 5/0693 (2013.01); C12N 2521/00 (2013.01);
Abstract
Methods for isolating viable cancer cells from a sample that comprises a mixture of cancerous cells and normal (non-cancerous) cells are provided. In the methods, a fluid preparation comprising a mixture of cancerous and normal cells is repeatedly exposed to fluid shear stresses, whereby the repeated exposure to the fluid shear stresses preferentially imparts fluid shear stress-resistance to the cancerous cells.