The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 9062087 B1

PDF
Full Text
Expired
Date of Patent:
Jun. 23, 2015

Filed:

Jan. 14, 2011
Applicants:

Guilong Zhao, Tianjin, CN;

Hua Shao, Tianjin, CN;

Weiren Xu, Tianjin, CN;

Wei Liu, Tianjin, CN;

Yuli Wang, Tianjin, CN;

Lida Tang, Tianjin, CN;

Chubing Tan, Tianjin, CN;

Bingni Liu, Tianjin, CN;

Shijun Zhang, Tianjin, CN;

Inventors:

Guilong Zhao, Tianjin, CN;

Hua Shao, Tianjin, CN;

Weiren Xu, Tianjin, CN;

Wei Liu, Tianjin, CN;

Yuli Wang, Tianjin, CN;

Lida Tang, Tianjin, CN;

Chubing Tan, Tianjin, CN;

Bingni Liu, Tianjin, CN;

Shijun Zhang, Tianjin, CN;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07H 7/04 (2006.01); C07H 7/06 (2006.01); A61K 31/70 (2006.01); A61K 31/351 (2006.01); C07D 309/10 (2006.01); C07D 409/10 (2006.01);
U.S. Cl.
CPC ...
C07H 7/04 (2013.01); C07H 7/06 (2013.01); A61K 31/351 (2013.01); A61K 31/70 (2013.01); C07D 309/10 (2013.01); C07D 409/10 (2013.01);
Abstract

The present invention relates to a sodium glucose cotransporter 2 (SGLT2) inhibitor with a phenyl C-glucoside structure, its preparation method, a pharmaceutical composition containing the same, and its use in treating diabetes and preparing an anti-diabetes medicament. The invention provides a compound with the structure of general formula I and a pharmaceutically acceptable salt and prodrug ester thereof, wherein, the definitions of Rand Rare selected from the following: (1) R5=R6=Me; (2) R5=Me, R6=OMe; (3) R5=Me, R6=H; (4) R5=Me, R6=F; (5) R5=F, R6=H; and (6) R5=OMe, R6=H.


Find Patent Forward Citations

Zhao, Guilong. (2015). Phenyl c-glucoside derivatives, preparation methods and uses thereof (U.S. Patent No. 9062087). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/9062087

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