The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 23, 2015
Filed:
Jan. 14, 2011
Guilong Zhao, Tianjin, CN;
Hua Shao, Tianjin, CN;
Weiren Xu, Tianjin, CN;
Wei Liu, Tianjin, CN;
Yuli Wang, Tianjin, CN;
Lida Tang, Tianjin, CN;
Chubing Tan, Tianjin, CN;
Bingni Liu, Tianjin, CN;
Shijun Zhang, Tianjin, CN;
Guilong Zhao, Tianjin, CN;
Hua Shao, Tianjin, CN;
Weiren Xu, Tianjin, CN;
Wei Liu, Tianjin, CN;
Yuli Wang, Tianjin, CN;
Lida Tang, Tianjin, CN;
Chubing Tan, Tianjin, CN;
Bingni Liu, Tianjin, CN;
Shijun Zhang, Tianjin, CN;
Tianjin Institute of Pharmaceutical Research, Tianjin, CN;
Abstract
The present invention relates to a sodium glucose cotransporter 2 (SGLT2) inhibitor with a phenyl C-glucoside structure, its preparation method, a pharmaceutical composition containing the same, and its use in treating diabetes and preparing an anti-diabetes medicament. The invention provides a compound with the structure of general formula I and a pharmaceutically acceptable salt and prodrug ester thereof, wherein, the definitions of Rand Rare selected from the following: (1) R5=R6=Me; (2) R5=Me, R6=OMe; (3) R5=Me, R6=H; (4) R5=Me, R6=F; (5) R5=F, R6=H; and (6) R5=OMe, R6=H.