The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 23, 2015
Filed:
Apr. 27, 2012
Jeffrey A. Robl, Newtown, PA (US);
Jun LI, Princeton, NJ (US);
Lawrence J. Kennedy, Titusville, NJ (US);
Steven J. Walker, Pennington, NJ (US);
Haixia Wang, Columbus, NJ (US);
William N. Washburn, Titusville, NJ (US);
Saleem Ahmad, Wall, NJ (US);
Khehyong Ngu, Pennington, NJ (US);
Jeffrey A. Robl, Newtown, PA (US);
Jun Li, Princeton, NJ (US);
Lawrence J. Kennedy, Titusville, NJ (US);
Steven J. Walker, Pennington, NJ (US);
Haixia Wang, Columbus, NJ (US);
William N. Washburn, Titusville, NJ (US);
Saleem Ahmad, Wall, NJ (US);
Khehyong Ngu, Pennington, NJ (US);
Bristol-Myers Squibb Company, Princeton, NJ (US);
Abstract
Novel compounds of Formula I:or an enantiomer, diastereomer, tautomer, prodrug or salt thereof, wherein m, Q, T, U, V, ring A, X, Y, R, R, R, R, R, R, R, R, R, R, and Rare defined herein, are provided which are TGR5 G protein-coupled receptor modulators. TGR5 G protein-coupled receptor modulators are useful in treating, preventing, or slowing the progression of diseases requiring TGR5 G protein-coupled receptor modulator therapy. Thus, the disclosure also concerns compositions comprising these novel compounds and methods of treating diseases or conditions related to the activity of the TGR5 G protein-coupled receptor by using any of these novel compounds or a composition comprising any of such novel compounds.