The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 23, 2015
Filed:
Nov. 29, 2012
Aurigene Discovery Technologies Limited, Bangalore, IN;
Um Pharmauji Sdn. Bhd, Kuala Lumpur, MY;
Mohamed Takhi, Hyderabad, IN;
Subramanya Hosahalli, Bangalore, IN;
Sunil Kumar Panigrahi, Kantamal, IN;
Muni Kumar Mahadari, Gadwal, IN;
Chandrashekar Reddy Kottam, Shadnagar, IN;
Noorsaadah Abd Rahman, Kuala Lumpur, MY;
Rohana Yusof, Kajang, MY;
Aurigene Discovery Technologies Limited, Bangalore, IN;
UM Pharmauji Sdn. BHD, Kuala Lumpur, MY;
Abstract
The present invention provides substituted pyridine derivatives of formula (I), which may be therapeutically useful as as anti-bacterial agents, more particularly FabI inhibitors. Formula (I) in which R1 to R5 and L have the meanings given in the specification, and pharmaceutically acceptable salts thereof that are useful in the treatment and prevention in diseases or disorder, in particular their use in diseases or disorder where there is an advantage anti-bacterial agents, more particularly FabI inhibitors. The present invention also provides methods for synthesizing and administering the FabI inhibitor compounds. The present invention also provides pharmaceutical formulations comprising at least one of the FabI inhibitor compounds together with a pharmaceutically acceptable carrier, diluent or excipient therefor.