The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 23, 2015

Filed:

Nov. 15, 2011
Applicants:

Martial Ruat, Orsay, FR;

Hélène Faure, Gif-sur-Yvette, FR;

Tatiana Gorojankina, Gif-sur-Yvette, FR;

André Mann, Ostwald, FR;

Maurizio Taddei, Monteriggioni, IT;

Fabrizio Manetti, Castelnuevo Berardenga, IT;

Antonio Solinas, Siena, IT;

Inventors:

Martial Ruat, Orsay, FR;

Hélène Faure, Gif-sur-Yvette, FR;

Tatiana Gorojankina, Gif-sur-Yvette, FR;

André Mann, Ostwald, FR;

Maurizio Taddei, Monteriggioni, IT;

Fabrizio Manetti, Castelnuevo Berardenga, IT;

Antonio Solinas, Siena, IT;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 215/22 (2006.01); A61K 31/4704 (2006.01); C07D 215/56 (2006.01);
U.S. Cl.
CPC ...
C07D 215/22 (2013.01); A61K 31/4704 (2013.01); C07D 215/56 (2013.01);
Abstract

The present invention relates to compounds which are quinolinone derivatives of general formula (I) capable of modulating the activity, in particular of inducing the differentiation, of stem and progenitor cells; these compounds are of use in the treatment of disorders related to a stem differentiation defect; the invention also relates to novel compounds among these quinolinone derivatives and to pharmaceutical compositions containing the same.


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