The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 23, 2015
Filed:
May. 22, 2008
Stefan Franzen, Apex, NC (US);
Richard Guenther, Cary, NC (US);
Steven A. Lommel, Cary, NC (US);
Lina Loo, Raleigh, NC (US);
Stefan Franzen, Apex, NC (US);
Richard Guenther, Cary, NC (US);
Steven A. Lommel, Cary, NC (US);
LiNa Loo, Raleigh, NC (US);
North Carolina State University, Raleigh, NC (US);
Abstract
This invention is a process for the manufacture of a plant viral capsid to be used for the targeted delivery of therapeutics to diseased cells. The process uses a plant virus as the starting material. The choice of the plant virus overcomes a problem in the manufacture of a uniform starting material. The final product has an advantage over other plant virus-based delivery systems in that the plant virus selected has a natural structure that is resistant to breakdown during the delivery process. This system takes advantage of the reversible divalent cation switch that this capsid employs to assemble and disassemble.