The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 23, 2015
Filed:
Oct. 15, 2010
Kwang Meyung Kim, Seoul, KR;
Ick Chan Kwon, Seoul, KR;
Kuiwon Choi, Seoul, KR;
Myung Sook Huh, Seoul, KR;
Seung Young Lee, Gyeonggi-Do, KR;
SO Jin Lee, Seoul, KR;
Kwang Meyung Kim, Seoul, KR;
Ick Chan Kwon, Seoul, KR;
Kuiwon Choi, Seoul, KR;
Myung Sook Huh, Seoul, KR;
Seung Young Lee, Gyeonggi-Do, KR;
So Jin Lee, Seoul, KR;
Abstract
Disclosed is a polymer-siRNA delivery carrier in which a siRNA is combined with a polymer and the use thereof. More specifically, there is disclosed a stable in vivo polymer-siRNA delivery carrier in which a polymer and a siRNA are combined by using charge interaction and biodegradable covalent bonding at the same time and the use thereof. The polymer-siRNA delivery carrier in which a polymer and a siRNA are combined by using charge interaction and biodegradable covalent bonding at the same time has a high siRNA deliver efficiency to a target portion in vivo. Hence, according to the polymer-siRNA binder, the siRNA for treatment can be effectively delivered to a target portion such as in vivo cancer tissue, and the like even with administration of a relatively low concentration, and thus widely used for the treatment of various kinds of diseases.