The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 23, 2015
Filed:
Sep. 16, 2014
Applicant:
Bluebird Bio, Inc., Cambridge, MA (US);
Inventors:
Maria Joann Denaro, Marblehead, MA (US);
Mitchell Howard Finer, Stow, MA (US);
Gabor Veres, Medford, MA (US);
Julian Down, Cambridge, MA (US);
Assignee:
BLUEBIRD BIO, INC., Cambridge, MA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/867 (2006.01); A61K 48/00 (2006.01); A61K 35/12 (2015.01); A61P 25/00 (2006.01); C12N 15/86 (2006.01); A61K 35/51 (2015.01); A61K 38/17 (2006.01); C12N 5/071 (2010.01); C12N 7/00 (2006.01); A61K 35/28 (2015.01); C07K 14/705 (2006.01);
U.S. Cl.
CPC ...
A61K 35/51 (2013.01); A61K 48/005 (2013.01); C07K 14/705 (2013.01); C12N 15/86 (2013.01); C12N 2740/16043 (2013.01); C12N 2800/24 (2013.01); C12N 2830/008 (2013.01); C12N 2830/50 (2013.01); C12N 2830/60 (2013.01); C12N 2840/00 (2013.01); C12N 2830/00 (2013.01); A61K 38/177 (2013.01); A61K 48/0058 (2013.01); C12N 5/0686 (2013.01); C12N 7/00 (2013.01); C12N 2740/15043 (2013.01); A61K 35/28 (2013.01);
Abstract
The present invention provides compositions comprising retroviral vectors, transduced cells, and methods of using the same for gene therapy. In particular, the present invention relates to lentiviral vectors and cells transduced with those vectors to provide gene therapy to subjects having an adrenoleukodystrophy and/or adrenomyeloneuropathy.