The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 23, 2015
Filed:
Nov. 02, 2011
Applicants:
Charles Kim, Cambridge, MA (US);
Takashi Nakai, Newton, MA (US);
Thomas Wai-ho Lee, Lexington, MA (US);
Joel Moore, Lexington, MA (US);
Nicholas Robert Perl, Brookline, MA (US);
Jason Rohde, Poolesville, MD (US);
Inventors:
Charles Kim, Cambridge, MA (US);
Takashi Nakai, Newton, MA (US);
Thomas Wai-Ho Lee, Lexington, MA (US);
Joel Moore, Lexington, MA (US);
Nicholas Robert Perl, Brookline, MA (US);
Jason Rohde, Poolesville, MD (US);
Assignee:
IRONWOOD PHARMACEUTICALS, INC., Cambridge, MA (US);
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/506 (2006.01); C07D 401/04 (2006.01); C07D 401/14 (2006.01); C07D 403/04 (2006.01); C07D 413/14 (2006.01); C07D 417/04 (2006.01); C07D 417/14 (2006.01); C07D 405/14 (2006.01); A61K 31/427 (2006.01); A61K 31/4439 (2006.01); A61K 31/444 (2006.01);
U.S. Cl.
CPC ...
A61K 31/506 (2013.01); C07D 401/04 (2013.01); C07D 401/14 (2013.01); C07D 403/04 (2013.01); C07D 413/14 (2013.01); C07D 417/04 (2013.01); C07D 417/14 (2013.01); C07D 405/14 (2013.01); A61K 31/427 (2013.01); A61K 31/4439 (2013.01); A61K 31/444 (2013.01);
Abstract
Compounds of Formula IA and Formula IB are described. They are useful as stimulators of sGC, particularly NO-independent, heme-dependent stimulators. These compounds may be useful for treating, preventing or managing various disorders that are herein disclosed.