The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 23, 2015

Filed:

Mar. 24, 2011
Applicant:

Manoj Maniar, Fremont, CA (US);

Inventor:

Manoj Maniar, Fremont, CA (US);

Assignee:

ONCONOVA THERAPEUTICS, INC, Newtown, NJ (US);

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/10 (2006.01); A61K 9/107 (2006.01); A61K 31/192 (2006.01); A61K 47/22 (2006.01); A61K 47/34 (2006.01); A61P 39/02 (2006.01); A61K 9/08 (2006.01);
U.S. Cl.
CPC ...
A61K 31/10 (2013.01); A61K 9/08 (2013.01); A61K 47/34 (2013.01); A61K 31/192 (2013.01); A61K 9/1075 (2013.01); A61K 47/22 (2013.01);
Abstract

An aqueous pharmaceutical solution composition comprising between about 20 mg/ml to about 100 mg/ml of a radioprotective α,β-unsaturated aryl sulfone, a cosolvent comprising polyethylene glycol (PEG), polypropylene glycol, polyglycerol, DMA, propylene glycol, glycerol, ethanol, sorbitol, isopropyl alcohol, or a combination thereof in an amount between about 25% and about 90% w/v, and a water soluble Vitamin E derivative, wherein the composition has a pH within the range of about 7.0 to about 9.5.


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