The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 23, 2015

Filed:

Nov. 09, 2007
Applicants:

Mary L. Disis, Renton, WA (US);

Vivian Goodell, San Diego, CA (US);

Hailing LU, Seattle, WA (US);

Douglas G. Mcneel, Madison, WI (US);

Inventors:

Mary L. Disis, Renton, WA (US);

Vivian Goodell, San Diego, CA (US);

Hailing Lu, Seattle, WA (US);

Douglas G. McNeel, Madison, WI (US);

Assignee:

UNIVERSITY OF WASHINGTON, Seattle, WA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/00 (2006.01); A61K 39/00 (2006.01); A61K 38/17 (2006.01); G01N 33/574 (2006.01);
U.S. Cl.
CPC ...
A61K 39/0011 (2013.01); A61K 39/0005 (2013.01); A61K 38/1754 (2013.01); A61K 38/1796 (2013.01); G01N 33/57488 (2013.01); G01N 2333/475 (2013.01); G01N 2333/65 (2013.01); G01N 2333/72 (2013.01); G01N 2800/52 (2013.01);
Abstract

The invention provides a method for inhibiting proliferation of cancer cells, as well as methods for detecting and treating various cancers, including cancer of the ovary, breast, prostate and colon. The method comprises contacting a cancer cell with an IGF-related molecule of the invention or administering an IGF-related vaccine to the cancer patient. In one embodiment, the molecule is an immunogenic peptide derived from IGFBP-2 or from IGF1 R. The invention additionally provides methods for detecting and treating cancer using IGF-related molecules.


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