The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 23, 2015

Filed:

Jul. 24, 2012
Applicants:

Yoichi Ishii, Miyazaki, JP;

Kazuyuki Ishii, Miyazaki, JP;

Inventors:

Yoichi Ishii, Miyazaki, JP;

Kazuyuki Ishii, Miyazaki, JP;

Assignee:

WELL STONE CO., Miyazaki, JP;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 36/62 (2006.01); A61K 8/98 (2006.01); A61Q 19/02 (2006.01); A61Q 19/00 (2006.01); A61K 8/02 (2006.01); A61K 35/62 (2006.01);
U.S. Cl.
CPC ...
A61K 8/98 (2013.01); A61Q 19/02 (2013.01); A61Q 19/00 (2013.01); A61K 8/987 (2013.01); A61K 8/022 (2013.01); A61K 35/62 (2013.01);
Abstract

The present invention provides a highly safe tyrosinase inhibitor having excellent tyrosinase-inhibiting action, and a method for producing the tyrosinase inhibitor. The method for producing a tyrosinase inhibitor comprises the steps of contacting a live earthworm with hydroxycarboxylic acid powder, diluting the resulting mixture with water to adjust the pH to 2 to 5, and then leaving the resulting dilution to stand for 3 to 180 minutes, or contacting a live earthworm with an aqueous solution of hydroxycarboxylic acid having a pH of 2 to 5 and then leaving the resulting mixture to stand for 3 to 180 minutes; followed by washing the live earthworm with water, grinding the washed earthworm, and then freeze-drying the obtained ground product.


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