The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 16, 2015
Filed:
Apr. 25, 2012
Applicant:
Kalim Mir, Cambridge, MA (US);
Inventor:
Kalim Mir, Cambridge, MA (US);
Assignee:
Singular Bio, Inc., San Francisco, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/68 (2006.01); C12P 19/34 (2006.01); C12M 1/34 (2006.01); C12M 3/00 (2006.01); C07H 21/02 (2006.01); C07H 21/04 (2006.01); G01N 33/58 (2006.01); B82Y 30/00 (2011.01); C12N 15/10 (2006.01); B82Y 10/00 (2011.01);
U.S. Cl.
CPC ...
G01N 33/582 (2013.01); B01J 2219/00497 (2013.01); B01J 2219/005 (2013.01); B01J 2219/00513 (2013.01); B01J 2219/0052 (2013.01); B01J 2219/00524 (2013.01); B01J 2219/00554 (2013.01); B01J 2219/00572 (2013.01); B01J 2219/00576 (2013.01); B01J 2219/00596 (2013.01); B01J 2219/00605 (2013.01); B01J 2219/0061 (2013.01); B01J 2219/00612 (2013.01); B01J 2219/00619 (2013.01); B01J 2219/00621 (2013.01); B01J 2219/00626 (2013.01); B01J 2219/0063 (2013.01); B01J 2219/00637 (2013.01); B01J 2219/00641 (2013.01); B01J 2219/00653 (2013.01); B01J 2219/00659 (2013.01); B01J 2219/0072 (2013.01); B82Y 10/00 (2013.01); B82Y 30/00 (2013.01); C12Q 1/6837 (2013.01); C12Q 1/6874 (2013.01); C12N 15/1065 (2013.01);
Abstract
Methods are provided for producing a molecular array comprising a plurality of molecules immoblised to a solid substrate at a density which allows individual immobilised molecules to be individually resolved, wherein each individual molecule in the array is spatially addressable and the identity of each molecule is known or determined prior to immobilisation. The use of spatially addressable low density molecular arrays in single molecule detection and analysis techniques is also provided. Novel assays and methods are also provided.