The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 16, 2015

Filed:

Jul. 22, 2011
Applicants:

Jung Weon Lee, Seoul, KR;

Ki Hun Park, Gyeongsangnam-do, KR;

Min Kyung Kang, Seoul, KR;

Inventors:

Jung Weon Lee, Seoul, KR;

Ki Hun Park, Gyeongsangnam-do, KR;

Min Kyung Kang, Seoul, KR;

Assignee:

SNU R&DB Foundation, Seoul, KR;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
G01N 33/563 (2006.01); A61K 39/395 (2006.01); A61K 39/00 (2006.01); G01N 33/68 (2006.01); G01N 33/50 (2006.01); A61K 31/18 (2006.01);
U.S. Cl.
CPC ...
G01N 33/563 (2013.01); G01N 33/6893 (2013.01); G01N 33/5067 (2013.01); G01N 2800/085 (2013.01); A61K 31/18 (2013.01);
Abstract

A composition for diagnosing, treating, and preventing liver disease, more particularly a composition for diagnosing liver disease comprising a material for measuring the grade of TM4SF5 (transmembrane 4 L six family member 5 or four-transmembrane L6 superfamily member 5) protein, a kit for diagnosing liver disease comprising the composition, a method for providing information necessary for diagnosing liver disease composed of the following steps: measuring the level of TM4SF5 protein and the expressions and phosphorylations of TM4SF5 expression related signaling proteins; and comparing the measured levels with those of the normal control, a method for screening a material for treating liver disease, and a composition for treating or preventing liver disease comprising a material inhibiting TM4SF5 protein expression or the expressions and phosphorylations of TM4SF5 expression related signaling proteins.


Find Patent Forward Citations

Loading…