The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 16, 2015
Filed:
May. 29, 2013
Methods of formulating and designing liquid drug suspensions containing ion exchange resin particles
Russell Mcmahen, Flower Mound, TX (US);
Mark Tengler, Colleyville, TX (US);
Michael Sloane, Forth Worth, TX (US);
Daniel Lockhart, Euless, TX (US);
Russell McMahen, Flower Mound, TX (US);
Mark Tengler, Colleyville, TX (US);
Michael Sloane, Forth Worth, TX (US);
Daniel Lockhart, Euless, TX (US);
NEOS THERAPEUTICS, LP, Grand Prairie, TX (US);
Abstract
The invention relates to the formulation and quality control of liquid drug suspensions. In particular, the invention relates to methods of formulating liquid suspensions comprising drug-containing resin particles. The invention also relates to methods of confirming the acceptability of drug-containing resin particles for use in formulating liquid drug suspensions. The invention further relates to methods of formulating liquid suspensions in which drug-containing resin particles, the liquid suspension, or both are modified to achieve a desired in vitro dissolution profile. The invention also relates to a novel dissolution method and methods of predicting in vivo bioequivalence based on in vitro dissolution methods.