The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 16, 2015

Filed:

Jan. 21, 2009
Applicants:

Marti Bartra Sanmartí, Barcelona, ES;

Ramón Berenguer Maimó, Barcelona, ES;

Jordi Benet-buchholz, Tarragona, ES;

Lluis Solà I Carandell, Altafulla, ES;

Inventors:

Marti Bartra Sanmartí, Barcelona, ES;

Ramón Berenguer Maimó, Barcelona, ES;

Jordi Benet-Buchholz, Tarragona, ES;

Lluis Solà I Carandell, Altafulla, ES;

Assignee:

ESTEVE QUIMICA, S.A., Barcelona, ES;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/52 (2006.01); C07D 473/16 (2006.01);
U.S. Cl.
CPC ...
C07D 473/16 (2013.01);
Abstract

Crystalline form of abacavir that is essentially free of solvent of formula (I), in particular crystalline Form I, and its preparation process which comprises the following steps: a) crystallizing abacavir from a solution of said compound in a (C-C)-alcohol, dichloromethane, acetonitrile/water, or mixtures thereof; b) isolating the crystalline form of abacavir that appears in the prior step; and c) removing the solvent from the crystalline form of abacavir thus obtained. Crystalline Form I can also be obtained by dispersion of abacavir in acetonitrile. The crystalline form of abacavir that is essentially free of solvent is useful for the preparation of pharmaceutical compositions for use in the treatment and/or prophylaxis of HIV infections.


Find Patent Forward Citations

Loading…