The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 16, 2015

Filed:

Jul. 06, 2012
Applicants:

Christina Hebach, Muenchenstein, CH;

Emilie Joly, Colmar, FR;

Joerg Kallen, Basel, CH;

James Gilbert Ternois, Kembs, FR;

Marina Tintelnot-blomley, Maulburg, DE;

Inventors:

Christina Hebach, Muenchenstein, CH;

Emilie Joly, Colmar, FR;

Joerg Kallen, Basel, CH;

James Gilbert Ternois, Kembs, FR;

Marina Tintelnot-Blomley, Maulburg, DE;

Assignee:

NOVARTIS AG, Basel, CH;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 271/06 (2006.01); C07D 413/12 (2006.01); C07D 413/10 (2006.01); A61K 31/5377 (2006.01); A61K 31/4439 (2006.01); A61K 31/454 (2006.01); A61K 31/4245 (2006.01); A61K 31/496 (2006.01);
U.S. Cl.
CPC ...
C07D 271/06 (2013.01); C07D 413/10 (2013.01); C07D 413/12 (2013.01); A61K 31/4245 (2013.01); A61K 31/4439 (2013.01); A61K 31/454 (2013.01); A61K 31/496 (2013.01); A61K 31/5377 (2013.01);
Abstract

The invention relates to novel trifluoromethyl-oxadiazole derivatives of formula (I), and pharmaceutically acceptable salts thereof, (I) in which all of the variables are as defined in the specification, pharmaceutical compositions thereof, pharmaceutical combinations thereof, and their use as medicaments, particularly for the treatment of neurodegeneration, muscle atrophy or metabolic syndrome via inhibition of HDAC4.


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