The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 16, 2015

Filed:

Dec. 05, 2014
Applicant:

Pfizer Inc., New York, NY (US);

Inventors:

Gary Erik Aspnes, Rockville, RI (US);

Mary Theresa Didiuk, Madison, CT (US);

Kevin James Filipski, Reading, MA (US);

Angel Guzman-Perez, Belmont, MA (US);

Jeffrey Allen Pfefferkorn, Acton, MA (US);

Benjamin Dawson Stevens, Cambridge, MA (US);

Meihua Mike Tu, Acton, MA (US);

Assignee:

Pfizer Inc., New York, NY (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 213/74 (2006.01); C07D 213/82 (2006.01); A61K 31/44 (2006.01); C07D 213/81 (2006.01); C07D 401/12 (2006.01); C07D 405/12 (2006.01);
U.S. Cl.
CPC ...
C07D 213/81 (2013.01); C07D 401/12 (2013.01); C07D 405/12 (2013.01); C07D 213/74 (2013.01); A61K 31/44 (2013.01); C07D 213/82 (2013.01);
Abstract

The present invention provides a compound of Formula (I) or a pharmaceutically acceptable salt thereof wherein R, R, R, A, A, A, A, L, B, B, Band Bare as defined herein. The compounds of Formula I have been found to act as glucagon antagonists or inverse agonists. Consequently, the compounds of Formula I and the pharmaceutical compositions thereof are useful for the treatment of diseases, disorders, or conditions mediated by glucagon.


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