The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 16, 2015
Filed:
Feb. 08, 2014
Applicant:
Pfizer Inc., New York, NY (US);
Inventors:
Antone John deBettencourt, III, Westerly, RI (US);
Peter Robert Rose, Ledyard, CT (US);
Evgenyi Shalaev, Dana Point, CA (US);
George Joseph Quallich, Venice, FL (US);
Carl Bernard Ziegler, East Lyme, CT (US);
Assignee:
Pfizer Inc., New York, NY (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 207/00 (2006.01); A61K 31/40 (2006.01); C07D 207/34 (2006.01); A61K 9/14 (2006.01); A61K 9/19 (2006.01);
U.S. Cl.
CPC ...
C07D 207/34 (2013.01); A61K 9/145 (2013.01); A61K 9/146 (2013.01); A61K 9/19 (2013.01); A61K 31/40 (2013.01);
Abstract
A process for forming amorphous atorvastatin comprising the steps of dissolving atorvastatin in a non-hydroxylic solvent and removing the solvent by freeze-drying, as well as processes of dissolving atorvastatin in a hydroxylic solvent with a solubilizing agent or an alkalizing agent or an antioxidant and removing the solvent by freeze-drying to afford amorphous atorvastatin.